Benefits of NAD+ Supplementation

The molecule NAD+ is found in every single cell in the body, and is important for efficient energy transfer from foods to tissues. NAD+ is also required for switching off genes responsible for speeding up the aging process.

From a cellular standpoint, lower levels of NAD+ reduce mitochondrial function, causing fewer ATP molecules to be produced, and fewer mitochondria being produced. This cycle results in manifestation of the many physical symptoms we call “aging”.

The age-related decrease in NAD+ causes deficiencies in both energy, and gene-related functions to accumulate. These defects accumulate to produce the disorders we typically identify with aging. The consequences of a decline in NAD+ levels and subsequent reduction in the SIRT 1 and SIRT 3 enzymes are:

  • ·       Neurodegeneration
  • ·       Vascular inflammation, which can lead to a heart attack
  • ·       Increased fat storage in the liver, which can lead fatty liver disease (NAFLD)
  • ·       Increased fat production and deposition in white adipose tissue, the primary fat storage form found in belly fat
  • ·       Insulin resistance, preventing cells from appropriately removing glucose from blood, producing high blood sugar levels and leading to diabetes
  • ·       Fatigue, and loss of muscle strength, resulting in reduced fatty acid oxidation, therefore depriving muscles of their normal sources of energy.

To avoid these degenerative processes, it is essential that steps be taken to optimize the amount of NAD+ in our bodies.

By increasing intracellular NAD+ levels, age-related mitochondrial dysfunction can be reversed. One of the ways to accomplish this is by engaging in major calorie restriction, which has been proven to raise NAD+ levels and in experimental organisms tested to date, to extend life span. But most people find significant calorie restriction to be nearly impossible in practice. This is where Nicotinamide riboside comes in.

This is a form of Vitamin B3 recently discovered by researchers, that converts to NAD+ in the body.

Vitamin B3 is involved in over 400 enzymatic reactions throughout the body and is absolutely essential for the production and management of cellular energy. Nicotinamide riboside been found to increase NAD+ levels and as a result, provide an extraordinary range of benefits that will change how we combat aging.

Boosting your NAD+ levels by supplementing with nicotinamide riboside presents a great new strategy for preventing the natural decline in cellular energy as we age, and promoting youthfulness.

Studies have shown that nicotinamide riboside switches “off” the genes of aging, extends life span, increases endurance, improves cognitive function, activates sirtuins, and enhances cellular energy. Together, these benefits add up to a system-wide slowing and reversal of certain aging processes. Nicotinamide riboside accomplishes this NAD+ boosting effect without the irritating skin flushing and rash caused by standard forms of vitamin B3.


Rahway, Scott. "The Youth Restoring Benefits Of NAD+." LifeExtension.com. Life Extension Magazine, Nov. 2014. Web. 15 July 2017.